Hspb1 and Tp53 Mutation and Expression Analysis in Cat Mammary Tumors

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Hspb1 and Tp53 Mutation and Expression Analysis in Cat Mammary Tumors

BACKGROUND Molecular marker based cancer diagnosis gaining more attention in the current genomics era. So, Hspb1 and Tp53 gene characterization and their mRNA expression might be helpful in diagnosis and prognosis of cat mammary adenocarcinoma. It will also add information in comparative cancer genetics and genomics. OBJECTIVES Eight tumors of Siamese cats were analyzed to ascertain germ-line...

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Mammary tumor associated Hspb1 mutation and screening of eight cat populations of the world

Current research highlights the Hspb1 based screening of eight cat populations of the world to investigate the association of newly found locus within cat mammary tumors. Total 180 cats were screened on the basis of Hspb1 4 bp deletion locus (1514-1517del4) which was observed in six mammary tumor cases in Siamese cat breed. Case-control association study revealed the non-significance with P=0.2...

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Mammary tumor associated Hspb1 mutation and screening of eight cat populations of the world

Current research highlights the Hspb1 based screening of eight cat populations of the world to investigate the association of newly found locus within cat mammary tumors. Total 180 cats were screened on the basis of Hspb1 4 bp deletion locus (1514-1517del4) which was observed in six mammary tumor cases in Siamese cat breed. Case-control association study revealed the non-significance with P=0.2...

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Expression Profiling of Hspb1 and Tp53 Genes through RT-qPCR in Different Cancer Types of Canis familiaris

Background: Diagnostic molecular marker studies are in vogue to have insight of most prevalent animal diseases including cancer.Objectives: Gene expression profi ling of pro and anti-apoptotic genes was conducted in dog Lymphoma, CTVT, SCC, granuloma, perianal adenocarcinoma and mammary tumors.Materials and Methods: Cancerous tissue...

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ژورنال

عنوان ژورنال: Iranian Journal of Biotechnology

سال: 2016

ISSN: 1728-3043,2322-2921

DOI: 10.15171/ijb.1480